CLOXACILLIN SODIUM

Cloxacillin sodium is a β-lactam antibiotic effective against penicillinase-producing staphylococci. Side effects include allergic reactions, nausea, and diarrhea.

SKU: afb4dc69b4bb Category: Tag:

Product Description


Mechanism of Action

Cloxacillin sodium is the rapidly absorbed salt form of cloxacillin. Mechanism identical: inhibition of bacterial cell‑wall crosslinking through PBP binding, resistant to penicillinase‑producing *Staphylococcus* strains.

Benefits and Advantages

Used in gram‑positive susceptibility studies, β‑lactamase‑resistant antibiotic modelling, PBP‑affinity assays and staphylococcal‑infection research.

Side Effects and Risks

Risks include allergic reactions, hepatic injury, GI discomfort and rare blood‑dyscrasias. Handle following β‑lactam handling protocols.

Datasheet


Molecular Formula

C19H17ClN3NaO5S

Molecular Weight

457.9 g/mol

CAS Number

642-78-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Cloxacillin sodium; 642-78-4; Sodium cloxacillin; Cloxacillin sodium anhydrous; Monosodium cloxacillin

IUPAC/Chemical Name

sodium (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChl Key

SCLZRKVZRBKZCR-SLINCCQESA-M

InChl Code

InChI=1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/23675320;

3D Conformer.

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