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Product Description
Mechanism of Action
Ciprofloxacin monohydrate is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. This prevents supercoiling, replication and chromosome segregation, producing bactericidal DNA damage. The monohydrate form provides enhanced stability for formulation and solid‑state studies.
Benefits and Advantages
Used in gyrase‑target studies, fluoroquinolone‑resistance modelling (QRDR mutations), antimicrobial PK/PD research, biofilm‑penetration assays and gram‑negative susceptibility profiling.
Side Effects and Risks
Risks include tendinopathy, QT prolongation, CNS effects, dysglycemia, phototoxicity and aortic aneurysm risk. Handle with high‑potency quinolone precautions.
Datasheet
| Molecular Formula | C17H18FN3O3÷H2O |
|---|---|
| Molecular Weight | 331.34 g/mol |
| CAS Number | 86393-32-0 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | ciprofloxacin; 85721-33-1; Ciprofloxacine; Ciprobay; Cipro |
| IUPAC/Chemical Name | 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid monohydrate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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