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Product Description
Mechanism of Action
Ceftibuten is a third‑generation oral cephalosporin with strong gram‑negative activity and resistance to many β‑lactamases. It binds PBPs and inhibits cell‑wall synthesis while demonstrating excellent stability in acidic environments. Highly active against Enterobacteriaceae and select respiratory pathogens.
Benefits and Advantages
Used in oral β‑lactam PK/PD modelling, community‑pathogen resistance studies, Enterobacteriaceae susceptibility profiling, β‑lactamase‑stability investigations and bioavailability research.
Side Effects and Risks
Risks include hypersensitivity, GI effects, dysbiosis and rare hepatic disturbances. Handle with antimicrobial PPE.
Datasheet
| Molecular Formula | C14H13N5O5S2 |
|---|---|
| Molecular Weight | 410.4 g/mol |
| CAS Number | 97519-39-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 7.05e-02 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | ceftibuten; 97519-39-6; Ceftibuteno; Ceftibutene; Ceftibutenum |
| IUPAC/Chemical Name | (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | UNJFKXSSGBWRBZ-BJCIPQKHSA-N |
| InChl Code | InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1 |
| References |
3D Conformer.
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