CEFTIBUTEN

Ceftibuten is an oral cephalosporin used for otitis media and bronchitis. Side effects include diarrhea, nausea, and abdominal pain. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 7e1e19cd3c83 Category: Tag:

Product Description


Mechanism of Action

Ceftibuten is a thirdgeneration oral cephalosporin with strong gramnegative activity and resistance to many lactamases. It binds PBPs and inhibits cellwall synthesis while demonstrating excellent stability in acidic environments. Highly active against Enterobacteriaceae and select respiratory pathogens.

Benefits and Advantages

Used in oral lactam PK/PD modelling, communitypathogen resistance studies, Enterobacteriaceae susceptibility profiling, lactamasestability investigations and bioavailability research.

Side Effects and Risks

Risks include hypersensitivity, GI effects, dysbiosis and rare hepatic disturbances. Handle with antimicrobial PPE.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H13N5O5S2

Molecular Weight

410.4 g/mol

CAS Number

97519-39-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

7.05e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

ceftibuten; 97519-39-6; Ceftibuteno; Ceftibutene; Ceftibutenum

IUPAC/Chemical Name

(6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChl Key

UNJFKXSSGBWRBZ-BJCIPQKHSA-N

InChl Code

InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/5282242;

3D Conformer.

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