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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Product Description
Mechanism of action
Cefpirome is a fourth‑generation cephalosporin with broad activity against gram-positive and gram-negative organisms, including resistant strains. It penetrates gram-negative outer membranes efficiently and binds PBPs with high affinity. It shows enhanced stability against many β‑lactamases and strong activity against hospital-acquired pathogens.
Benefits and advantages
Used in resistant-gram-negative research, β‑lactamase-mechanism modelling, ICU infection studies, PK/PD modelling, advanced cephalosporin SAR analysis and biofilm-inhibition research.
Side effects and risks
Risks include hypersensitivity, infusion reactions, hepatic disturbances, neurotoxicity (rare) and GI upset. Handle using high-potency β‑lactam antimicrobial containment.
Datasheet
| Molecular Formula | C22H22N8O5S·H2SO4 |
|---|---|
| Molecular Weight | 612.7 g/mol |
| CAS Number | 98753-19-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cefpirome sulfate; 98753-19-6; Cefrom; HR 810 sulfate; HR-810 Sulfate |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;sulfuric acid |
| InChl Key | RKTNPKZEPLCLSF-QHBKFCFHSA-N |
| InChl Code | InChI=1S/C22H22N6O5S2.H2O4S/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27;1-5(2,3)4/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32);(H2,1,2,3,4)/b26-15-;/t16-,20-;/m1./s1 |
| References |
3D Conformer.
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