CEFADROXIL

Cefadroxil is a first‑generation cephalosporin with broad gram‑positive activity. Benefits include good oral absorption. Side effects include GI upset and allergic reactions.

SKU: c638a76f6595 Category: Tag:

Product Description


Mechanism of Action

Cefadroxil is a first-generation cephalosporin antibiotic with strong gram-positive activity. It inhibits PBPs, preventing cell-wall crosslinking and peptidoglycan formation. Cefadroxil exhibits extended half-life due to enhanced renal tubular reabsorption, allowing less frequent dosing.

Benefits and Advantages

Used in gram-positive susceptibility testing, β-lactam structure–activity research, PBP-binding assays, oral cephalosporin pharmacokinetic modelling and staphylococcal cell-wall studies.

Side Effects and Risks

Risks include hypersensitivity, diarrhoea, dysbiosis, eosinophilia, and rare hepatic effects. Handle as a β-lactam antibiotic.

Datasheet


Molecular Formula

C16H17N3O5S

Molecular Weight

363.4 g/mol

CAS Number

50370-12-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

cefadroxil; 50370-12-2; Cephadroxil; Cefadroxil anhydrous; Cefadroxilo

IUPAC/Chemical Name

(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChl Key

BOEGTKLJZSQCCD-UEKVPHQBSA-N

InChl Code

InChI=1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/47965;

3D Conformer.

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