About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cefaclor is a second-generation oral cephalosporin antibiotic that inhibits bacterial cell-wall synthesis by binding to penicillin-binding proteins (PBPs). This blocks transpeptidation of peptidoglycan layers, causing weakening of the bacterial cell wall and lysis. Cefaclor has enhanced stability against certain -lactamases and improved gram-negative activity compared with first-generation agents.
Benefits and Advantages
Used in -lactam mechanism studies, PBP-affinity profiling, gram-negative antibacterial research, -lactamase-resistance modelling, comparative cephalosporin SAR studies, and biofilm-inhibition assays.
Side Effects and Risks
Risks include hypersensitivity, rash, serum sicknesslike reactions, GI upset and rare haemolytic anaemia. Handle with -lactam antimicrobial precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H14ClN3O4S |
|---|---|
| Molecular Weight | 367.8 g/mol |
| CAS Number | 53994-73-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cefaclor; 53994-73-3; Cephaclor; Ceclor; Cefaclor anhydrous |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | QYIYFLOTGYLRGG-GPCCPHFNSA-N |
| InChl Code | InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1 |
| References |
3D Conformer.
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