AMPICILLIN

Ampicillin acts by inhibiting bacterial cell wall synthesis and is used for respiratory, urinary, and GI infections. Side effects include diarrhea, rash, and hypersensitivity.

SKU: 2af08a5c8e6f Category: Tag:

Product Description


Mechanism of action

Ampicillin acts by binding to PBPs and inhibiting bacterial cell wall transpeptidation. It is active against many Gram-positive organisms and selected Gram-negative bacilli.

Benefits and advantages

Serves as a benchmark β‑lactam in microbiology, genetic plasmid selection (amp‑resistance markers), and resistance mechanism studies.

Side effects and risks

Hypersensitivity, GI disturbance, rash and rare hepatic dysfunction. Laboratory PPE required.

Datasheet


Molecular Formula

C16H19N3O4S

Molecular Weight

349.4 g/mol

CAS Number

69-53-4

Storage Condition

Ampicillin capsules and powder for oral suspension should be stored in tight containers @ 15-30 °C. Following reconstitution, oral suspensions of either anhydrous ampicillin or ampicillin trihydrate should preferable be refrigerated @ 2-8 °C but are stable for 7 days @ room temperature or 14 days @ 2-8 °C.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

ampicillin; 69-53-4; Aminobenzylpenicillin; Ampicillin acid; Ampicilline

IUPAC/Chemical Name

(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

AVKUERGKIZMTKX-NJBDSQKTSA-N

InChl Code

InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/6249;

3D Conformer.

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