AMPICILLIN
Ampicillin acts by inhibiting bacterial cell wall synthesis and is used for respiratory, urinary, and GI infections. Side effects include diarrhea, rash, and hypersensitivity.
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Product Description
Mechanism of action
Ampicillin acts by binding to PBPs and inhibiting bacterial cell wall transpeptidation. It is active against many Gram-positive organisms and selected Gram-negative bacilli.
Benefits and advantages
Serves as a benchmark β‑lactam in microbiology, genetic plasmid selection (amp‑resistance markers), and resistance mechanism studies.
Side effects and risks
Hypersensitivity, GI disturbance, rash and rare hepatic dysfunction. Laboratory PPE required.
Datasheet
| Molecular Formula | C16H19N3O4S |
|---|---|
| Molecular Weight | 349.4 g/mol |
| CAS Number | 69-53-4 |
| Storage Condition | Ampicillin capsules and powder for oral suspension should be stored in tight containers @ 15-30 °C. Following reconstitution, oral suspensions of either anhydrous ampicillin or ampicillin trihydrate should preferable be refrigerated @ 2-8 °C but are stable for 7 days @ room temperature or 14 days @ 2-8 °C. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ampicillin; 69-53-4; Aminobenzylpenicillin; Ampicillin acid; Ampicilline |
| IUPAC/Chemical Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChl Key | AVKUERGKIZMTKX-NJBDSQKTSA-N |
| InChl Code | InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1 |
| References |
3D Conformer.
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