AMOXICILLIN

Amoxicillin is a broadspectrum penicillin that inhibits bacterial cell wall synthesis. Benefits include strong efficacy. Side effects include rash, diarrhea, and rare hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: ec002b16488c Category: Tag:

Product Description


Mechanism of action

Amoxicillin is a semi-synthetic aminopenicillin that inhibits transpeptidation during bacterial cell wall synthesis. By binding penicillin-binding proteins (PBPs), it prevents formation of cross-linked peptidoglycan, leading to cell lysis in actively dividing bacteria.

Benefits and advantages

Due to its broad spectrum and consistent behaviour, amoxicillin is widely used in antimicrobial susceptibility testing, beta-lactamase inhibition studies and drug-resistance modelling. Its predictable PK profile makes it ideal for benchmarking new lactam analogues.

Side effects and risks

Allergy, rash, anaphylaxis, GI upset and rare hepatic injury. Must be handled under biosafety conditions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H19N3O5S

Molecular Weight

365.4 g/mol

CAS Number

26787-78-0

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 – 8 °C.

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

amoxicillin; Amoxycillin; 26787-78-0; Amoxicillin anhydrous; Amoxicilline

IUPAC/Chemical Name

(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

LSQZJLSUYDQPKJ-NJBDSQKTSA-N

InChl Code

InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/33613;

3D Conformer.

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