AMOXICILLIN
Amoxicillin is a broadspectrum penicillin that inhibits bacterial cell wall synthesis. Benefits include strong efficacy. Side effects include rash, diarrhea, and rare hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Amoxicillin is a semi-synthetic aminopenicillin that inhibits transpeptidation during bacterial cell wall synthesis. By binding penicillin-binding proteins (PBPs), it prevents formation of cross-linked peptidoglycan, leading to cell lysis in actively dividing bacteria.
Benefits and advantages
Due to its broad spectrum and consistent behaviour, amoxicillin is widely used in antimicrobial susceptibility testing, beta-lactamase inhibition studies and drug-resistance modelling. Its predictable PK profile makes it ideal for benchmarking new lactam analogues.
Side effects and risks
Allergy, rash, anaphylaxis, GI upset and rare hepatic injury. Must be handled under biosafety conditions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H19N3O5S |
|---|---|
| Molecular Weight | 365.4 g/mol |
| CAS Number | 26787-78-0 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 – 8 °C. |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | amoxicillin; Amoxycillin; 26787-78-0; Amoxicillin anhydrous; Amoxicilline |
| IUPAC/Chemical Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| InChl Key | LSQZJLSUYDQPKJ-NJBDSQKTSA-N |
| InChl Code | InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1 |
| References |
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