MEPHENYTOIN

Mephenytoin is an antiepileptic affecting sodium channel firing and metabolized variably among individuals. Side effects include rash, blood dyscrasias, and sedation. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 8fdd3f9cb122 Category: Tag:

Product Description


Mechanism of Action

MEPHENYTOIN displays a broad and multiaxis biochemical interaction profile characterised by modulation of enzymatic networks, receptormediated signalling, intracellular ion regulation, mitochondrial bioenergetics and transcriptional pathway governance. Its structural features suggest interactions with catalytic and regulatory proteins, leading to changes in phosphorylation cycles, metabolic flux, mitochondrial redox balance, calciumsignalling behaviour and stressresponse activation. Depending on cellular environment and concentration, the compound may act as an activator, inhibitor or regulatory modulator.

Benefits and Advantages

This compound supports a wide range of , including:

  • Receptorligand affinity profiling and bindingsite mapping
  • Enzymecascade modelling and catalyticdomain interaction studies
  • Mitochondrialfunction assays, oxidativestress evaluation and metabolicflux tracking
  • Transcriptomic, proteomic and metabolomic investigation for pathway mapping
  • Apoptosis / autophagy pathway research and cellularstress modelling
  • Highresolution mechanismofaction studies and SAR exploration

Side Effects and Risks

Potential risks include oxidative imbalance, mitochondrial overload, ionchannel dysregulation, receptor crosstalk, cytoskeletal disruption and dosedependent cytotoxicity. At elevated exposure levels, the compound may induce apoptosis, autophagy, inflammatory signalling, metabolic reprogramming or transcriptional instability. Proper laboratory controls and strict biosafety procedures are required for handling.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C12H14N2O2

Molecular Weight

218.25 g/mol

CAS Number

50-12-4

Storage Condition

Store below 40 °C (104 °F), preferably between 15 and 30 °C (59 and 86 °F), unless otherwise specified by manufacturer. Store in a well-closed container.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

MEPHENYTOIN; 50-12-4; Mesantoin; Methoin; Methylphenetoin

IUPAC/Chemical Name

5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione

InChl Key

GMHKMTDVRCWUDX-UHFFFAOYSA-N

InChl Code

InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)

References

https://pubchem.ncbi.nlm.nih.gov/compound/4060;

3D Conformer.

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