About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Fumazinil (Ro 15‑1788 analogue) is a benzodiazepine‑site ligand that acts predominantly as an antagonist or partial inverse agonist at the benzodiazepine binding site of GABA‑A receptors. By displacing benzodiazepine agonists from their allosteric site, it reduces their potentiation of GABA‑mediated chloride currents and normalizes inhibitory tone.
Benefits and Advantages
Used in GABA‑A receptor pharmacology, benzodiazepine‑binding studies, receptor‑occupancy assays, and research on anxiolytic/hypnotic reversal.
Side Effects and Risks
May precipitate withdrawal, anxiety, agitation, seizures (in heavily sedated or dependent subjects) and autonomic activation. Handle with CNS‑active receptor‑ligand precautions.
Datasheet
| Molecular Formula | C10H11NO3 |
|---|---|
| Molecular Weight | 193.2 g/mol |
| CAS Number | 534-37-8 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | Methyl 2-aminobenzoate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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