About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Fludrocortisone is a potent mineralocorticoid receptor agonist that enhances sodium reabsorption and potassium excretion, modulating electrolyte and fluid balance.
Benefits and Advantages
Used in adrenalaxis modelling, mineralocorticoid signalling research and reninangiotensinaldosterone studies.
Side Effects and Risks
Hypertension, edema, hypokalemia and metabolic alkalosis.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H29FO5 |
|---|---|
| Molecular Weight | 380.4 g/mol |
| CAS Number | 127-31-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | In water, 140 mg/L at 25 °C |
| Purity | Purity information is available upon request (COA). |
| Synonym | fludrocortisone; 127-31-1; Astonin-H; Alflorone; Fluohydrisone |
| IUPAC/Chemical Name | (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
| InChl Key | AAXVEMMRQDVLJB-BULBTXNYSA-N |
| InChl Code | InChI=1S/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1 |
| References |
3D Conformer.
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