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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Fludrocortisone is a potent mineralocorticoid receptor agonist that enhances sodium reabsorption and potassium excretion, modulating electrolyte and fluid balance.
Benefits and Advantages
Used in adrenal‑axis modelling, mineralocorticoid signalling research and renin‑angiotensin‑aldosterone studies.
Side Effects and Risks
Hypertension, edema, hypokalemia and metabolic alkalosis.
Datasheet
| Molecular Formula | C21H29FO5 |
|---|---|
| Molecular Weight | 380.4 g/mol |
| CAS Number | 127-31-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | In water, 140 mg/L at 25 °C |
| Purity | Purity information is available upon request (COA). |
| Synonym | fludrocortisone; 127-31-1; Astonin-H; Alflorone; Fluohydrisone |
| IUPAC/Chemical Name | (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
| InChl Key | AAXVEMMRQDVLJB-BULBTXNYSA-N |
| InChl Code | InChI=1S/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1 |
| References |
3D Conformer.
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