FLUCYTOSINE

Flucytosine is an antifungal converted to 5fluorouracil inside fungal cells, inhibiting DNA/RNA synthesis. Side effects include bone marrow suppression and hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 347980c014e7 Category: Tag:

Product Description


Mechanism of Action

Flucytosine is a fluorinated pyrimidine antifungal that converts intracellularly to 5FU, inhibiting DNA and RNA synthesis in susceptible fungi.

Benefits and Advantages

Used in fungal nucleotidesynthesis studies, synergistic antifungal research and RNAinterference pathway modelling.

Side Effects and Risks

Risks include hepatotoxicity, bonemarrow suppression and GI toxicity.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C4H4FN3O

Molecular Weight

129.09 g/mol

CAS Number

2022-85-7

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

5-Fluorocytosine; flucytosine; 2022-85-7; Fluorocytosine; Ancobon

IUPAC/Chemical Name

6-amino-5-fluoro-1H-pyrimidin-2-one

InChl Key

XRECTZIEBJDKEO-UHFFFAOYSA-N

InChl Code

InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3366;

3D Conformer.

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