About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Etoricoxib is a selective COX‑2 inhibitor that reduces prostaglandin synthesis involved in inflammation, pain transmission and fever. Its high COX‑2/COX‑1 selectivity aims to minimize GI toxicity associated with nonselective NSAIDs.
Benefits and Advantages
Used in COX‑2 selectivity assays, inflammation‑biology research, prostaglandin‑pathway modelling, and selective‑NSAID comparative studies.
Side Effects and Risks
Risks include increased cardiovascular risk, hypertension, edema and rare GI complications. Handle with selective‑COX‑2 inhibitor precautions.
Datasheet
| Molecular Formula | C18H15ClN2O2S |
|---|---|
| Molecular Weight | 358.8 g/mol |
| CAS Number | 202409-33-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 3.28e-03 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | Etoricoxib; 202409-33-4; Arcoxia; MK-0663; 5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine |
| IUPAC/Chemical Name | 5-chloro-2-(6-methyl-3-pyridinyl)-3-(4-methylsulfonylphenyl)pyridine |
| InChl Key | MNJVRJDLRVPLFE-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3 |
| References |
3D Conformer.
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