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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Etoposide phosphate is a watersoluble prodrug of etoposide that is rapidly dephosphorylated in vivo. It improves formulation flexibility and reduces infusionrelated reactions compared with standard etoposide.
Benefits and Advantages
Used in prodrugconversion studies, aqueousformulation development, topoisomeraseII research, and cancercell cytotoxicity assays.
Side Effects and Risks
Risks include myelosuppression, infusionsite irritation, hypotension and alopecia. Handle with cytotoxicprodrug precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C29H33O16P |
|---|---|
| Molecular Weight | 668.5 g/mol |
| CAS Number | 117091-64-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ETOPOSIDE PHOSPHATE; 117091-64-2; Etopofos; Etopophos; BMY-40481 |
| IUPAC/Chemical Name | [4-[(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-9-yl]-2,6-dimethoxyphenyl] dihydrogen phosphate |
| InChl Key | LIQODXNTTZAGID-OCBXBXKTSA-N |
| InChl Code | InChI=1S/C29H33O16P/c1-11-38-9-20-27(42-11)23(30)24(31)29(43-20)44-25-14-7-17-16(40-10-41-17)6-13(14)21(22-15(25)8-39-28(22)32)12-4-18(36-2)26(19(5-12)37-3)45-46(33,34)35/h4-7,11,15,20-25,27,29-31H,8-10H2,1-3H3,(H2,33,34,35)/t11-,15+,20-,21-,22+,23-,24-,25-,27-,29+/m1/s1 |
| References |
3D Conformer.
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