ETOMIDATE

Etomidate is an anesthetic that enhances GABAergic activity, providing rapid induction with minimal cardiovascular depression. Side effects include adrenal suppression, myoclonus, and nausea. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 9da21937c5c3 Category: Tag:

Product Description


Mechanism of Action

Etomidate is an imidazolederived intravenous anesthetic that enhances GABAA receptor activity at 2/3 subunits. It induces rapid hypnosis with minimal cardiovascular depression due to minimal effects on sympathetic tone. Etomidate also transiently inhibits adrenal 11hydroxylase.

Benefits and Advantages

Used in anestheticmechanism research, GABAA subtype pharmacology, endocrinesuppression studies, and rapidinduction modelling.

Side Effects and Risks

Risks include adrenal suppression, myoclonus, nausea, injectionsite pain and rare seizures. Handle with IVanesthetic precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H16N2O2

Molecular Weight

244.29 g/mol

CAS Number

33125-97-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Etomidate; 33125-97-2; Hypnomidate; (+)-Etomidate; Amidate

IUPAC/Chemical Name

ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate

InChl Key

NPUKDXXFDDZOKR-LLVKDONJSA-N

InChl Code

InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/667484;

3D Conformer.

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