ERGOTIDINE
Ergotidine is an ergot derivative acting on adrenergic and serotonergic receptors with vascular effects. Side effects include GI upset, vasospasm, and dizziness.
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Product Description
Mechanism of Action
Ergotidine is a hydrogenated ergot alkaloid with dopaminergic and adrenergic receptor activity. Hydrogenation reduces some vasoconstrictive properties while preserving complex receptor interactions that influence vascular tone and neuroendocrine signalling.
Benefits and Advantages
Used in comparative ergot‑alkaloid pharmacology, receptor‑selectivity profiling, cerebrovascular‑tone modelling, and dopaminergic/adrenergic pathway research.
Side Effects and Risks
Risks include residual vasospasm, GI upset, headache and potential ergot‑related toxicity at high exposures. Handle with standard ergot‑alkaloid precautions.
Datasheet
| Molecular Formula | C5H9N3 |
|---|---|
| Molecular Weight | 111.15 g/mol |
| CAS Number | 51-45-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | COLORLESS LONG PRISMATIC CRYSTALS; ODORLESS; 1 G SOL IN ABOUT 4 ML WATER; AQ SOLN IS ACID TO LITMUS; WHEN DRIED AT 105 °C FOR 2 HR, IT MELTS AT ABOUT 140 °C /PHOSPHATE/ |
| Purity | Purity information is available upon request (COA). |
| Synonym | histamine; 51-45-6; 2-(1H-imidazol-5-yl)ethanamine; Ergamine; Ergotidine |
| IUPAC/Chemical Name | 2-(1H-imidazol-5-yl)ethanamine |
| InChl Key | NTYJJOPFIAHURM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) |
| References |
3D Conformer.
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