ERGOTIDINE

Ergotidine is an ergot derivative acting on adrenergic and serotonergic receptors with vascular effects. Side effects include GI upset, vasospasm, and dizziness.

SKU: 57de5dfd2ddd Category: Tag:

Product Description


Mechanism of Action

Ergotidine is a hydrogenated ergot alkaloid with dopaminergic and adrenergic receptor activity. Hydrogenation reduces some vasoconstrictive properties while preserving complex receptor interactions that influence vascular tone and neuroendocrine signalling.

Benefits and Advantages

Used in comparative ergot‑alkaloid pharmacology, receptor‑selectivity profiling, cerebrovascular‑tone modelling, and dopaminergic/adrenergic pathway research.

Side Effects and Risks

Risks include residual vasospasm, GI upset, headache and potential ergot‑related toxicity at high exposures. Handle with standard ergot‑alkaloid precautions.

Datasheet


Molecular Formula

C5H9N3

Molecular Weight

111.15 g/mol

CAS Number

51-45-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

COLORLESS LONG PRISMATIC CRYSTALS; ODORLESS; 1 G SOL IN ABOUT 4 ML WATER; AQ SOLN IS ACID TO LITMUS; WHEN DRIED AT 105 °C FOR 2 HR, IT MELTS AT ABOUT 140 °C /PHOSPHATE/

Purity

Purity information is available upon request (COA).

Synonym

histamine; 51-45-6; 2-(1H-imidazol-5-yl)ethanamine; Ergamine; Ergotidine

IUPAC/Chemical Name

2-(1H-imidazol-5-yl)ethanamine

InChl Key

NTYJJOPFIAHURM-UHFFFAOYSA-N

InChl Code

InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

References

https://pubchem.ncbi.nlm.nih.gov/compound/774;

3D Conformer.

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