ERGOCRYSTIN BASE
Ergocrystin base is an ergot derivative with dopaminergic and vasomodulatory activity. Side effects include dizziness, nausea, and cold extremities.
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Product Description
Mechanism of Action
Ergocrystin is a naturally occurring ergot peptide alkaloid that interacts with dopamine D₂, serotonin 5‑HT₁/5‑HT₂ and adrenergic α receptors. It exhibits partial agonism and antagonism depending on receptor subtype and tissue, influencing vasomotor tone and pituitary hormone secretion.
Benefits and Advantages
Used in polypharmacologic receptor‑profiling research, dopaminergic/serotonergic signalling studies, vascular‑reactivity assays, and ergot‑alkaloid structure–activity analyses.
Side Effects and Risks
Risks include peripheral vasoconstriction, hypertension, GI disturbances, headache and chronic ergot toxicity with overexposure. Handle cautiously as a bioactive ergot alkaloid.
Datasheet
| Molecular Formula | C35H39N5O5 |
|---|---|
| Molecular Weight | 581.66 g/mol |
| CAS Number | 511-40-8 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | (5'α)-12'-hydroxy-2'-methyl-5'-(propan-2-yl)ergoline-8-carboxamide |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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