DROXICAM

Droxicam is an oxicam NSAID reducing inflammation and pain by COX inhibition. Side effects include GI irritation, headache, and renal strain. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d70390314dff Category: Tag:

Product Description


Mechanism of Action

Droxicam is an oxicamclass NSAID and a prodrug of piroxicam. It inhibits COX1 and COX2 enzymes, reducing prostaglandin synthesis and attenuating inflammation, pain and fever. The prodrug structure improves GI tolerability.

Benefits and Advantages

Used in COXenzyme inhibition studies, NSAID SAR modelling, inflammatorymediator research, and prodrugactivation pharmacology.

Side Effects and Risks

Risks include GI irritation, renal impairment, hypersensitivity reactions, increased bleeding tendency and rare hepatotoxicity. Handle with NSAIDclass precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C14H11N3O5S2

Molecular Weight

357.3 g/mol

CAS Number

90101-16-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Droxicam; 90101-16-9; Droxicamum; F24ADO1E2D; DTXSID70238035

IUPAC/Chemical Name

5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione

InChl Key

OEHFRZLKGRKFAS-UHFFFAOYSA-N

InChl Code

InChI=1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/65679;

3D Conformer.

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