About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Drofnine hydrochloride is an antispasmodic and analgesic compound that reduces smoothmuscle contraction by modulating intracellular Ca²⁺ dynamics and inhibiting phosphodiesterasemediated cAMP breakdown. It exhibits mild anticholinergic activity and direct myotropic relaxation.
Benefits and Advantages
Used in smoothmuscle physiology studies, visceralpain modelling, GI motility research, and Cahandling pathway assays.
Side Effects and Risks
Risks include dizziness, dry mouth, mild hypotension, tachycardia and anticholinergic effects at higher doses. Handle with antispasmodiccompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H25NO2·HCl |
|---|---|
| Molecular Weight | 353.9 g/mol |
| CAS Number | 548-66-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | >53.1 [ug/mL] (The mean of the results at pH 7.4) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Drofenine hydrochloride; 548-66-3; Cycloadiphenine hydrochloride; Drofenine HCl; IT-19 |
| IUPAC/Chemical Name | 2-(diethylamino)ethyl 2-cyclohexyl-2-phenylacetate;hydrochloride |
| InChl Key | WIELVDXKOYPANK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H31NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5,7-8,11-12,18-19H,3-4,6,9-10,13-16H2,1-2H3;1H |
| References |
3D Conformer.
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