DITHIOSTEINE
Dithiosteine is a mucolytic reducing mucus viscosity via sulfhydryl activity. Benefits include improved airway clearance. Side effects include nausea and mild irritation.
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Product Description
Mechanism of Action
Dithiosteine is a sulfur‑containing amino‑acid derivative with mucolytic and antioxidant properties. Its free thiol groups can cleave disulfide bonds in mucus glycoproteins, reducing viscosity and enhancing mucociliary clearance. It also contributes to redox buffering and can influence glutathione‑related pathways.
Benefits and Advantages
Used in mucus‑rheology research, antioxidant and thiol‑chemistry studies, respiratory‑clearance modelling, and disulfide‑bond cleavage assays.
Side Effects and Risks
Risks include GI discomfort, unpleasant odor, sulfur‑related sensitivity and rare hypersensitivity reactions. Handle with thiol‑compound precautions.
Datasheet
| Molecular Formula | C8H11NO4S2 |
|---|---|
| Molecular Weight | 249.3 g/mol |
| CAS Number | 84611-23-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Erdosteine; 84611-23-4; RV-144; Erdosteinum; Mucotec |
| IUPAC/Chemical Name | 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid |
| InChl Key | QGFORSXNKQLDNO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H11NO4S2/c10-6(3-14-4-7(11)12)9-5-1-2-15-8(5)13/h5H,1-4H2,(H,9,10)(H,11,12) |
| References |
3D Conformer.
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