DIENESTROL
Dienestrol is a synthetic estrogen used for menopausal symptoms and vaginal atrophy. Side effects include nausea, breast tenderness, and increased thrombotic risk. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dienestrol is a synthetic nonsteroidal estrogen (stilbene class) that binds estrogen receptors ER and ER, activating estrogenresponsive gene transcription. It mimics endogenous estradiol and modulates reproductive and metabolic pathways.
Benefits and Advantages
Used in estrogenreceptor studies, endocrinesignalling research, hormoneresponsive gene assays, and reproductivebiology modelling.
Side Effects and Risks
Risks include thromboembolic reactions, endometrial hyperplasia, breast tenderness, fluid retention and nausea. Handle with hormonemodulating precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H18O2 |
|---|---|
| Molecular Weight | 266.3 g/mol |
| CAS Number | 84-17-3 |
| Storage Condition | Commercially available dienestrol vaginal cream should be stored at a temperature less than 40 °C, preferably between 15-30 °C; freezing should be avoided. |
| Solubility | 1.23e-02 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | dienestrol; Dienoestrol; Dehydrostilbestrol; Cycladiene; Dienol |
| IUPAC/Chemical Name | 4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol |
| InChl Key | NFDFQCUYFHCNBW-SCGPFSFSSA-N |
| InChl Code | InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+ |
| References |
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