DESOGESTREL

Desogestrel is a progestin that inhibits ovulation and thickens cervical mucus, providing effective contraception. Benefits include favorable cycle control. Side effects may include acne, mood changes, and irregular bleeding. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d53c0277efb1 Category: Tag:

Product Description


Mechanism of Action

Desogestrel is a thirdgeneration progestin that is converted to the active metabolite etonogestrel. It binds progesterone receptors, suppresses luteinizing hormone (LH) surges, inhibits ovulation, thickens cervical mucus, and modifies endometrial receptivity. Its androgenic activity is low, making it useful for hormonalregulation research.

Benefits and Advantages

Used in reproductiveendocrinology modelling, ovulationsuppression studies, progesteronereceptor signalling analysis, hormonalcontraception mechanism research and metabolichormone profiling.

Side Effects and Risks

Risks include thromboembolic events, mood changes, irregular bleeding, breast tenderness and metabolic shifts. Handle with hormonemodulating compound precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C22H30O

Molecular Weight

310.5 g/mol

CAS Number

54024-22-5

Storage Condition

Keep container tightly closed in a dry and well-ventilated place.

Solubility

<1 mg/ml

Purity

Purity information is available upon request (COA).

Synonym

DESOGESTREL; 54024-22-5; Cerazette; Desogestrelum; Org-2969

IUPAC/Chemical Name

(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

InChl Key

RPLCPCMSCLEKRS-BPIQYHPVSA-N

InChl Code

InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/40973;

3D Conformer.

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