DESOGESTREL
Desogestrel is a progestin that inhibits ovulation and thickens cervical mucus, providing effective contraception. Benefits include favorable cycle control. Side effects may include acne, mood changes, and irregular bleeding.
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Product Description
Mechanism of Action
Desogestrel is a third‑generation progestin that is converted to the active metabolite etonogestrel. It binds progesterone receptors, suppresses luteinizing hormone (LH) surges, inhibits ovulation, thickens cervical mucus, and modifies endometrial receptivity. Its androgenic activity is low, making it useful for hormonal‑regulation research.
Benefits and Advantages
Used in reproductive‑endocrinology modelling, ovulation‑suppression studies, progesterone‑receptor signalling analysis, hormonal‑contraception mechanism research and metabolic‑hormone profiling.
Side Effects and Risks
Risks include thromboembolic events, mood changes, irregular bleeding, breast tenderness and metabolic shifts. Handle with hormone‑modulating compound precautions.
Datasheet
| Molecular Formula | C22H30O |
|---|---|
| Molecular Weight | 310.5 g/mol |
| CAS Number | 54024-22-5 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. |
| Solubility | <1 mg/ml |
| Purity | Purity information is available upon request (COA). |
| Synonym | DESOGESTREL; 54024-22-5; Cerazette; Desogestrelum; Org-2969 |
| IUPAC/Chemical Name | (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol |
| InChl Key | RPLCPCMSCLEKRS-BPIQYHPVSA-N |
| InChl Code | InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1 |
| References |
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