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Product Description
Mechanism of Action
Desmopressin acetate is the stabilized acetate salt of desmopressin, improving formulation and stability in biological systems. Its mechanism mirrors desmopressin, acting as a Vreceptor agonist to increase aquaporin2 trafficking and enhance water retention, while augmenting endothelial release of hemostatic factors.
Benefits and Advantages
Used in renalwater handling studies, hemostaticresponse assays, endocrine modelling, Vreceptor binding research and drugformulation stability investigations.
Side Effects and Risks
Risks include hyponatremia, water intoxication, edema, nasal irritation (intranasal route), headache and GI discomfort. Handle with vasopressinanalogue precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C52H74N16O15S2 |
|---|---|
| Molecular Weight | 1129.3 g/mol |
| CAS Number | 62288-83-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Desmopressin acetate; Octostim; Stimate; Desmopressin acetate anhydrous; CONCENTRAID |
| IUPAC/Chemical Name | acetic acid;(2S)-N-[(2R)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide |
| InChl Key | MLSVJHOYXJGGTR-IFHOVBQLSA-N |
| InChl Code | InChI=1S/C46H64N14O12S2.C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);1H3,(H,3,4)/t28-,29+,30+,31+,32+,33+,34+;/m1./s1 |
| References |
3D Conformer.
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