DEOXYADENOSINE
Demethylchlortetracycline is a tetracycline‑class antibiotic that inhibits bacterial protein synthesis by binding the 30S ribosomal subunit. It has been used in acne and other infections. Side effects include photosensitivity, GI upset, and risk of tooth discoloration or altered bone growth with long‑term use.
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Product Description
Mechanism of Action
Deoxyadenosine is a purine nucleoside composed of adenine linked to deoxyribose. It is a fundamental substrate for DNA synthesis and is phosphorylated to dATP. Elevated intracellular levels of dATP inhibit ribonucleotide reductase and trigger apoptosis in lymphocytes—central to adenosine‑deaminase deficiency pathology.
Benefits and Advantages
Used in DNA‑synthesis modelling, purine‑metabolism research, immunodeficiency pathway studies, enzyme‑kinetic assays and nucleoside‑transport investigations.
Side Effects and Risks
Risks include metabolic imbalance, lymphotoxicity at high concentrations and irritation upon exposure. Handle with biochemical‑substrate precautions.
Datasheet
| Molecular Formula | C10H13N5O3 |
|---|---|
| Molecular Weight | 251.24 g/mol |
| CAS Number | 958-09-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 2'-deoxyadenosine; deoxyadenosine; 958-09-8; 2-Deoxyadenosine; Adenyldeoxyriboside |
| IUPAC/Chemical Name | (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
| InChl Key | OLXZPDWKRNYJJZ-RRKCRQDMSA-N |
| InChl Code | InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1 |
| References |
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