DEHYDROPREGNENOLONE ACETATE
Delorazepam is a long‑acting benzodiazepine that enhances GABAergic inhibition, providing anxiolytic, sedative, and anticonvulsant effects. Benefits include sustained symptom control in anxiety disorders. Side effects include drowsiness, cognitive slowing, dependence, and withdrawal risk with prolonged use.
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Product Description
Mechanism of Action
Dehydropregnenolone acetate is a stabilized ester of pregnenolone, a neuroactive steroid precursor involved in synthesis of progesterone, glucocorticoids, mineralocorticoids and androgens. It modulates NMDA, GABA‑A and sigma‑1 receptors while affecting neuroinflammation and mitochondrial signalling pathways. Esterification enhances stability and controlled release.
Benefits and Advantages
Used in neurosteroid‑pathway modelling, pregnenolone‑conversion studies, neuroinflammation assays, neurocognitive research and steroidogenic enzyme analysis.
Side Effects and Risks
Risks include endocrine disruption, sedation or stimulation (dose‑dependent), GI irritation and hormonal imbalance. Handle with neurosteroid‑compound precautions.
Datasheet
| Molecular Formula | C23H32O3 |
|---|---|
| Molecular Weight | 356.5 g/mol |
| CAS Number | 979-02-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 16-Dehydropregnenolone acetate; 979-02-2; Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate; 832VMW7ZGC |
| IUPAC/Chemical Name | [(3S,8R,9S,10R,13S,14S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate |
| InChl Key | MZWRIOUCMXPLKV-RFOVXIPZSA-N |
| InChl Code | InChI=1S/C23H32O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21H,6,8-13H2,1-4H3/t17-,18-,20-,21-,22-,23+/m0/s1 |
| References |
3D Conformer.
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