CYTISINE
Cytisine is a plant-derived alkaloid and partial agonist of neuronal nicotinic acetylcholine receptors, especially alpha4beta2 receptors. It is used in pharmaceutical research into smoking-cessation pharmacology, receptor signalling and nicotinic ligand selectivity. Possible risks include nausea, dizziness, headache, sleep disturbance and cardiovascular effects in sensitive subjects. Only GMP materials will be supplied, logistics all according to GDP.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cytisine is a plant-derived alkaloid that acts mainly as a partial agonist at neuronal nicotinic acetylcholine receptors, especially the alpha4beta2 subtype. By providing moderate receptor stimulation while competing with nicotine, it can reduce reinforcement signals and support controlled investigation of nicotinic receptor pathways.
Benefits and Advantages
Cytisine is valuable in studies of smoking-cessation pharmacology, receptor selectivity, dopaminergic signalling and structure-activity relationships within nicotinic ligands. Its defined alkaloid structure and established pharmacological profile make it suitable for comparative work with nicotine and varenicline-like compounds.
Side Effects and Risks
Reported risks include nausea, gastrointestinal discomfort, dry mouth, headache, dizziness, sleep disturbance and possible cardiovascular effects in sensitive subjects. It should be handled as a bioactive alkaloid and evaluated only under appropriate professional and regulatory controls.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C11H14N2O |
|---|---|
| Molecular Weight | 190.24 g/mol |
| CAS Number | 485-35-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Soluble in methanol and ethanol; solubility depends on solvent and conditions. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cytisine; Cytisinicline; Baptitoxine; Sophorine; Tabex |
| IUPAC/Chemical Name | (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one |
| InChl Key | ANJTVLIZGCUXLD-DTWKUNHWSA-N |
| InChl Code | InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1 |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/10235; small-molecule |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
