CYPROTERONE ACETATE

Cyproheptadine HCl is an antihistamine blocking H1 receptors, also used to stimulate appetite. Side effects include drowsiness, dry mouth, and weight gain.

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Product Description


Mechanism of Action

Cyproterone acetate is a steroidal antiandrogen that competes with dihydrotestosterone (DHT) at androgen receptors and suppresses gonadotropin release via progesterone‑like negative feedback. It reduces androgen‑dependent growth and signalling.

Benefits and Advantages

Used in androgen‑receptor studies, hormone‑suppression modelling, endocrine‑disorder research, and antiandrogenic compound SAR analysis.

Side Effects and Risks

Risks include hepatotoxicity, thromboembolic events, fatigue, gynecomastia, mood changes and endocrine disturbance. Handle with hormone‑modulating‑agent precautions.

Datasheet


Molecular Formula

C24H29ClO4

Molecular Weight

416.9 g/mol

CAS Number

427-51-0

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 – 8 °C

Solubility

Very soluble in dichloromethane and acetone; soluble in methanol; sparingly soluble in ethanol.

Purity

Purity information is available upon request (COA).

Synonym

CYPROTERONE ACETATE; 427-51-0; Androcur; Cyproterone 17-O-acetate; Cyprostat

IUPAC/Chemical Name

[(1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-2,16-dimethyl-6-oxo-15-pentacyclo[9.7.0.02,8.03,5.012,16]octadeca-7,9-dienyl] acetate

InChl Key

UWFYSQMTEOIJJG-FDTZYFLXSA-N

InChl Code

InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/9880;

3D Conformer.

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