About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cotarnine is a benzylisoquinoline alkaloid derived from opium‑related biosynthetic pathways. It exhibits cholinergic‑modulating, smooth‑muscle regulating and mild vasodilatory activity. It interacts with muscarinic signalling and may inhibit phosphodiesterase pathways.
Benefits and Advantages
Used in natural‑product SAR research, smooth‑muscle pharmacology, cholinergic‑signal modulation studies, alkaloid biosynthesis modelling and vascular‑tone investigations.
Side Effects and Risks
Risks include hypotension, dizziness, mild hepatotoxicity and cholinergic disturbances. Handle as an isoquinoline alkaloid with CNS and vascular effects.
Datasheet
| Molecular Formula | C12H13NO3 |
|---|---|
| Molecular Weight | 219.24 g/mol |
| CAS Number | 483-17-0 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | Desmethylemetine; 1-[(3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl)methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol; Dihydropsychotrine; Emetan-6'-ol, 7',10,11-trimethoxy-; orb1992074 |
| IUPAC/Chemical Name | 1-(3,4-dimethoxybenzyl)-6,7-dihydroisoquinolin-5-ol |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
