COLESTILAN
Colestilan is a polymeric binder that reduces phosphate absorption in chronic kidney disease. Side effects include constipation, nausea, and abdominal discomfort. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Colestilan is a nonabsorbed anionexchange resin that binds phosphate, bile acids and certain uremic toxins in the GI tract. It reduces intestinal phosphate absorption and modulates bileacid signalling, providing benefits in mineral metabolism and lipid regulation.
Benefits and Advantages
Used in chronickidneydisease phosphatebinding research, bileacid sequestration modelling, resinbinding studies, guttoxicity removal experiments and metabolic homeostasis research.
Side Effects and Risks
Risks include constipation, nausea, GI discomfort and interference with oral drug absorption. Handle with polymeric resin safety precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C7H11ClN2O |
|---|---|
| Molecular Weight | 174.63 g/mol |
| CAS Number | 95522-45-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Colestilan; 95522-45-5; colestilanum; RefChem:1082113; 2-(chloromethyl)oxirane;2-methyl-1H-imidazole |
| IUPAC/Chemical Name | 2-(chloromethyl)oxirane;2-methyl-1H-imidazole |
| InChl Key | DEMLYXMVPJAVFU-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C4H6N2.C3H5ClO/c1-4-5-2-3-6-4;4-1-3-2-5-3/h2-3H,1H3,(H,5,6);3H,1-2H2 |
| References |
3D Conformer.
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