CLOXIQUINE
Cloxyquin is an antimicrobial agent historically used for skin and eye infections. Side effects include local irritation, discoloration, and rare hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Cloxyquine is a halogenated quinoline derivative with broad antiparasitic and antimicrobial properties. Its mechanism involves interference with nucleicacid synthesis, disruption of protozoal membrane integrity, and chelation of metal ions essential for microbial enzymatic activity. Its lipophilic structure enables accumulation within parasitic vacuoles, enhancing intracellular antimicrobial action.
Benefits and Advantages
Used in protozoalmodel research, quinolineSAR studies, helminthpathway investigations, intracellular penetration assays, and evaluation of metalchelation antimicrobial mechanisms.
Side Effects and Risks
Risks include hepatotoxicity, GI irritation, neurotoxicity, hypersensitivity and retinal disturbances (classrelated quinoline effects). Handle with antiparasiticcompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H6ClNO |
|---|---|
| Molecular Weight | 179.60 g/mol |
| CAS Number | 130-16-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-CHLORO-8-HYDROXYQUINOLINE; 130-16-5; 5-Chloroquinolin-8-ol; cloxyquin; Cloxiquine |
| IUPAC/Chemical Name | 5-chloroquinolin-8-ol |
| InChl Key | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H |
| References |
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