About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cloxazepine is a benzodiazepinerelated compound acting as a positive allosteric modulator of the GABA_A receptor. It enhances GABAmediated chloride influx, producing anxiolytic, sedative and anticonvulsant effects.
Benefits and Advantages
Used in GABA_A receptor pharmacology, anxiolyticscreening assays, seizurethreshold modelling, behaviouralneuroscience research and benzodiazepine SAR studies.
Side Effects and Risks
Risks include sedation, dependence, cognitive impairment, respiratory depression and withdrawal symptoms. Handle with benzodiazepineclass precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C22H24ClN3O5 |
|---|---|
| Molecular Weight | 445.9 g/mol |
| CAS Number | 27833-64-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Loxapine succinate; 27833-64-3; Loxapac; Cloxazepin; Daxolin |
| IUPAC/Chemical Name | butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
| InChl Key | YQZBAXDVDZTKEQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H18ClN3O.C4H6O4/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18;5-3(6)1-2-4(7)8/h2-7,12H,8-11H2,1H3;1-2H2,(H,5,6)(H,7,8) |
| References |
3D Conformer.
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