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Product Description
Mechanism of Action
Cloxazepine is a benzodiazepine‑related compound acting as a positive allosteric modulator of the GABA_A receptor. It enhances GABA‑mediated chloride influx, producing anxiolytic, sedative and anticonvulsant effects.
Benefits and Advantages
Used in GABA_A receptor pharmacology, anxiolytic‑screening assays, seizure‑threshold modelling, behavioural‑neuroscience research and benzodiazepine SAR studies.
Side Effects and Risks
Risks include sedation, dependence, cognitive impairment, respiratory depression and withdrawal symptoms. Handle with benzodiazepine‑class precautions.
Datasheet
| Molecular Formula | C22H24ClN3O5 |
|---|---|
| Molecular Weight | 445.9 g/mol |
| CAS Number | 27833-64-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Loxapine succinate; 27833-64-3; Loxapac; Cloxazepin; Daxolin |
| IUPAC/Chemical Name | butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
| InChl Key | YQZBAXDVDZTKEQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H18ClN3O.C4H6O4/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18;5-3(6)1-2-4(7)8/h2-7,12H,8-11H2,1H3;1-2H2,(H,5,6)(H,7,8) |
| References |
3D Conformer.
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