About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Clocinizine hydrochloride is a firstgeneration Hantihistamine with anticholinergic and sedative properties. It blocks H receptors, reducing histaminemediated vasodilation, itch and allergic responses.
Benefits and Advantages
Used in allergypathway research, histaminereceptor modelling, antihistamine SAR studies and sedativeantihistamine comparisons.
Side Effects and Risks
Risks include sedation, cognitive impairment, anticholinergic effects and dizziness. Handle as a CNSpenetrant antihistamine.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H21ClN2 |
|---|---|
| Molecular Weight | 475.9 g/mol |
| CAS Number | 39245-23-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Clocinizine hydrochloride; 39245-23-3; AE8KM1QU3Q; Clorcinnazine dihydrochloride; 4-Cinnamyl-1-[(4-chlorophenyl)benzyl]piperazine dihydrochloride |
| IUPAC/Chemical Name | 1-[(4-chlorophenyl)-phenylmethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride |
| InChl Key | YFQRGPYJACKPRU-WRQJSNHTSA-N |
| InChl Code | InChI=1S/C26H27ClN2.2ClH/c27-25-15-13-24(14-16-25)26(23-11-5-2-6-12-23)29-20-18-28(19-21-29)17-7-10-22-8-3-1-4-9-22;;/h1-16,26H,17-21H2;2*1H/b10-7+;; |
| References |
3D Conformer.
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