CLOCAPRAMINE HCL

Clocapramine hydrochloride is an antidepressant modulating serotonergic and noradrenergic transmission. Side effects include sedation, weight gain, and hypotension.

SKU: 083cec7fd08a Category: Tag:

Product Description


Mechanism of Action

Clocapramine hydrochloride is a tricyclic antidepressant with serotonin‑reuptake inhibitory effects and mild dopamine‑modulating activity. It alters synaptic monoamine levels, influencing mood, affect and anxiety pathways.

Benefits and Advantages

Used in antidepressant pharmacology, monoamine‑transport studies, behavioural‑modelling research and tricyclic SAR analysis.

Side Effects and Risks

Risks include anticholinergic effects, sedation, arrhythmias, weight gain and serotonin‑syndrome potential. Handle with CNS‑active compound precautions.

Datasheet


Molecular Formula

C21H29Cl2N3

Molecular Weight

572.0 g/mol

CAS Number

65016-29-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

clocapramine hydrochloride; Clocapramine dihydrochloride monohydrate; 9NLU6H3LRD; Y-4153; 65016-29-7

IUPAC/Chemical Name

1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide;hydrate;dihydrochloride

InChl Key

SWCNPPOGIXOVAZ-UHFFFAOYSA-N

InChl Code

InChI=1S/C28H37ClN4O.2ClH.H2O/c29-24-12-11-23-10-9-22-7-2-3-8-25(22)33(26(23)21-24)18-6-15-31-19-13-28(14-20-31,27(30)34)32-16-4-1-5-17-32;;;/h2-3,7-8,11-12,21H,1,4-6,9-10,13-20H2,(H2,30,34);2*1H;1H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/71300452;

3D Conformer.

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