CLOCAPRAMINE HCL
Clocapramine hydrochloride is an antidepressant modulating serotonergic and noradrenergic transmission. Side effects include sedation, weight gain, and hypotension.
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Product Description
Mechanism of Action
Clocapramine hydrochloride is a tricyclic antidepressant with serotonin‑reuptake inhibitory effects and mild dopamine‑modulating activity. It alters synaptic monoamine levels, influencing mood, affect and anxiety pathways.
Benefits and Advantages
Used in antidepressant pharmacology, monoamine‑transport studies, behavioural‑modelling research and tricyclic SAR analysis.
Side Effects and Risks
Risks include anticholinergic effects, sedation, arrhythmias, weight gain and serotonin‑syndrome potential. Handle with CNS‑active compound precautions.
Datasheet
| Molecular Formula | C21H29Cl2N3 |
|---|---|
| Molecular Weight | 572.0 g/mol |
| CAS Number | 65016-29-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | clocapramine hydrochloride; Clocapramine dihydrochloride monohydrate; 9NLU6H3LRD; Y-4153; 65016-29-7 |
| IUPAC/Chemical Name | 1-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide;hydrate;dihydrochloride |
| InChl Key | SWCNPPOGIXOVAZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C28H37ClN4O.2ClH.H2O/c29-24-12-11-23-10-9-22-7-2-3-8-25(22)33(26(23)21-24)18-6-15-31-19-13-28(14-20-31,27(30)34)32-16-4-1-5-17-32;;;/h2-3,7-8,11-12,21H,1,4-6,9-10,13-20H2,(H2,30,34);2*1H;1H2 |
| References |
3D Conformer.
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