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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Clocinizine hydrochloride is a first‑generation H₁‑antihistamine with anticholinergic and sedative properties. It blocks H₁ receptors, reducing histamine‑mediated vasodilation, itch and allergic responses.
Benefits and Advantages
Used in allergy‑pathway research, histamine‑receptor modelling, antihistamine SAR studies and sedative‑antihistamine comparisons.
Side Effects and Risks
Risks include sedation, cognitive impairment, anticholinergic effects and dizziness. Handle as a CNS‑penetrant antihistamine.
Datasheet
| Molecular Formula | C17H21ClN2 |
|---|---|
| Molecular Weight | 475.9 g/mol |
| CAS Number | 39245-23-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Clocinizine hydrochloride; 39245-23-3; AE8KM1QU3Q; Clorcinnazine dihydrochloride; 4-Cinnamyl-1-[(4-chlorophenyl)benzyl]piperazine dihydrochloride |
| IUPAC/Chemical Name | 1-[(4-chlorophenyl)-phenylmethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride |
| InChl Key | YFQRGPYJACKPRU-WRQJSNHTSA-N |
| InChl Code | InChI=1S/C26H27ClN2.2ClH/c27-25-15-13-24(14-16-25)26(23-11-5-2-6-12-23)29-20-18-28(19-21-29)17-7-10-22-8-3-1-4-9-22;;/h1-16,26H,17-21H2;2*1H/b10-7+;; |
| References |
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