About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cimetidine hydrochloride is the stable, water‑soluble salt widely used in research and clinical formulations. Mechanism identical: H₂‑receptor blockade on parietal cells reduces gastric acid secretion. Also notable for potent CYP inhibition affecting many drugs.
Benefits and Advantages
Used in solution‑stability studies, H₂‑receptor pharmacology, CYP450 inhibition screening, gastric‑physiology experiments and acid‑suppression modelling.
Side Effects and Risks
Risks include anti‑androgenic effects, hepatic dysfunction, CNS disturbances and extensive drug‑interaction risk. Handle with acid‑secretion‑modulator precautions.
Datasheet
| Molecular Formula | C10H17ClN6S |
|---|---|
| Molecular Weight | 288.80 g/mol |
| CAS Number | 70059-30-2 |
| Storage Condition | Preserve in tight, light resistant containers at controlled room temperatures. |
| Solubility | 5 mg/mL at 68 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cimetidine hydrochloride; 70059-30-2; Cimetidine Hcl; WF10491673; DTXSID10990302 |
| IUPAC/Chemical Name | 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine;hydrochloride |
| InChl Key | QJHCNBWLPSXHBL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H |
| References | PubChem; ChemBL; FDA; |
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