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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cilostazol is a phosphodiesterase‑III (PDE‑3) inhibitor that increases intracellular cAMP in vascular smooth muscle and platelets. This causes vasodilation, inhibition of platelet aggregation and improved microvascular perfusion. It also modulates inflammatory pathways and endothelial nitric oxide production.
Benefits and Advantages
Used in vascular‑biology research, platelet‑activation studies, cAMP‑signalling research, peripheral‑artery‑disease modelling and PDE‑inhibitor SAR investigations.
Side Effects and Risks
Risks include tachycardia, palpitations, headache, diarrhoea, bleeding risk and contraindications in heart‑failure models. Handle with PDE‑inhibitor precautions.
Datasheet
| Molecular Formula | C20H27N5O2 |
|---|---|
| Molecular Weight | 369.5 g/mol |
| CAS Number | 73963-72-1 |
| Storage Condition | Store Pletal tablets at 25 °C (77 °F); excursions permitted to 15-30 °C (59-86 °F). |
| Solubility | Practically insoluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | cilostazol; 73963-72-1; Pletal; Cilostazole; Pletaal |
| IUPAC/Chemical Name | 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one |
| InChl Key | RRGUKTPIGVIEKM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26) |
| References | PubChem; ChemBL; FDA; |
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