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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of Action
Chlorzoxazone is a centrally acting skeletal muscle relaxant that depresses polysynaptic reflex arcs in the spinal cord. It reduces excessive skeletal‑muscle tone without directly affecting neuromuscular junction transmission. Its mechanism involves enhancement of inhibitory interneuron activity and modulation of GABAergic signalling.
Benefits and Advantages
Used in muscle‑spasm modelling, CNS-depressant mechanism studies, spinal‑reflex research, comparative muscle‑relaxant pharmacology and drug‑interaction metabolism studies (notably CYP2E1).
Side Effects and Risks
Risks include hepatotoxicity (idiosyncratic), sedation, dizziness, GI discomfort and impaired psychomotor coordination. Handle as a CNS depressant with hepatotoxic potential.
Datasheet
| Molecular Formula | C7H4ClNO2 |
|---|---|
| Molecular Weight | 169.56 g/mol |
| CAS Number | 95-25-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | chlorzoxazone; 95-25-0; Paraflex; 5-Chloro-2-benzoxazolone; 5-Chloro-2(3H)-benzoxazolone |
| IUPAC/Chemical Name | 5-chloro-3H-1,3-benzoxazol-2-one |
| InChl Key | TZFWDZFKRBELIQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10) |
| References |
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