CHLOROLPYRAMINE

Chlorolpyramine is an antihistamine relieving allergic rhinitis and urticaria by blocking H1 receptors. Side effects include drowsiness, dry mouth, and mild dizziness. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of Action

Chloropyramine is a firstgeneration Hantihistamine with anticholinergic, analgesic and mild adrenergicblocking properties. It competitively inhibits H receptors, decreasing histamineinduced vasodilation, capillary permeability and allergic symptoms. It readily crosses the bloodbrain barrier, producing sedative CNS effects.

Benefits and Advantages

Used in allergy research, histaminesignalling modelling, antihistamine SAR studies, anaphylaxispathway exploration, and CNSpenetrant antihistamine comparisons.

Side Effects and Risks

Risks include sedation, anticholinergic effects, hypotension, dizziness and rare cardiac conduction disturbances. Handle as a potent sedating antihistamine.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H20ClN3

Molecular Weight

289.8 g/mol

CAS Number

6170-42-9

Storage Condition

Store in a cool, dry place; protected from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

Chloropyramine; Halopyramine; Chlorpyramine; 59-32-5; Chlorneoantergan

IUPAC/Chemical Name

N-[2-(dimethylamino)ethyl]-N-pyridin-2-yl-4-chlorobenzenesulfonamide

InChl Key

QZVNWZQNKUJOGH-UHFFFAOYSA-N

InChl Code

InChI=1S/C16H20ClN3/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14/h3-10H,11-13H2,1-2H3

References

PubChem; ChemBL; FDA substance registry;

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