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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chlorohemin (hemin chloride) is an ironcontaining porphyrin complex mimicking the prosthetic group of hemoproteins. It modulates hemeoxygenase1 (HO1) expression, influences oxidativestress responses, and participates in electrontransfer and catalytic reactions. Chlorohemin is widely used as a biochemical reagent for studying hemedependent processes.
Benefits and Advantages
Used in hemeprotein research, oxidativestress modelling, HO1 pathway studies, cytochrome biochemistry, ironmetabolism analysis, and enzymecatalysis assays.
Side Effects and Risks
Risks include oxidative damage, skin/eye irritation, iron overload (systemic exposure) and photosensitization. Handle with hemeprotein reagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C34H32ClFeN4O4 |
|---|---|
| Molecular Weight | 651.9 g/mol |
| CAS Number | 16009-13-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | RefChem:1093269; Npc76529; hemin; Chlorohemin; Panhematin |
| IUPAC/Chemical Name | 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride |
| InChl Key | BTIJJDXEELBZFS-UHFFFAOYSA-K |
| InChl Code | InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3 |
| References |
3D Conformer.
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