CHLOROHEMIN
Chlorohemin is a heme derivative used in biochemical research to study cytochrome activity. Side effects relate to laboratory exposure, including irritation or oxidative stress.
About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chlorohemin (hemin chloride) is an iron‑containing porphyrin complex mimicking the prosthetic group of hemoproteins. It modulates heme‑oxygenase‑1 (HO‑1) expression, influences oxidative‑stress responses, and participates in electron‑transfer and catalytic reactions. Chlorohemin is widely used as a biochemical reagent for studying heme‑dependent processes.
Benefits and Advantages
Used in heme‑protein research, oxidative‑stress modelling, HO‑1 pathway studies, cytochrome biochemistry, iron‑metabolism analysis, and enzyme‑catalysis assays.
Side Effects and Risks
Risks include oxidative damage, skin/eye irritation, iron overload (systemic exposure) and photosensitization. Handle with heme‑protein reagent precautions.
Datasheet
| Molecular Formula | C34H32ClFeN4O4 |
|---|---|
| Molecular Weight | 651.9 g/mol |
| CAS Number | 16009-13-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | RefChem:1093269; Npc76529; hemin; Chlorohemin; Panhematin |
| IUPAC/Chemical Name | 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(3+);chloride |
| InChl Key | BTIJJDXEELBZFS-UHFFFAOYSA-K |
| InChl Code | InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.


