About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Cabergoline is a long-acting dopamine D₂ receptor agonist that powerfully suppresses prolactin secretion from pituitary lactotrophs. It reduces intracellular cAMP, inhibits prolactin gene transcription and restores dopaminergic tone. It also affects nigrostriatal dopaminergic pathways.
Benefits and advantages
Used in prolactin-regulation research, pituitary-adenoma studies, dopaminergic signalling analysis, Parkinsonism modelling and ergoline SAR investigations.
Side effects and risks
Risks include nausea, hypotension, valvulopathy (with chronic use), dizziness, hallucinations and impulse-control disturbances. Handle under dopaminergic-agonist precautions.
Datasheet
| Molecular Formula | C26H37N5O2 |
|---|---|
| Molecular Weight | 451.6 g/mol |
| CAS Number | 81409-90-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | cabergoline; 81409-90-7; Dostinex; Cabaser; Cabergolina |
| IUPAC/Chemical Name | (6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
| InChl Key | KORNTPPJEAJQIU-KJXAQDMKSA-N |
| InChl Code | InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
