BAMIFYLLIN

Benzocaine is a topical anesthetic blocking sodium channels for surface anesthesia. Benefits include quick onset. Side effects include methemoglobinemia at high doses and rare allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of action

Bamifyllin is a xanthine derivative with moderate phosphodiesterase inhibition and adenosinereceptor antagonism. These effects lead to increased intracellular cAMP, bronchodilation and improved respiratory airflow. Bamifyllin exhibits greater airway selectivity and fewer cardiac effects than older xanthines like theophylline.

Benefits and advantages

Used in respiratory pharmacology, xanthine SAR studies, PDEinhibition modelling, adenosinereceptor research and airwaysmoothmuscle physiology investigations.

Side effects and risks

Risks include nausea, headache, mild CNS stimulation, arrhythmias at high concentrations and tremor. Handle with methylxanthineappropriate laboratory precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H22N4O3

Molecular Weight

385.5 g/mol

CAS Number

2016-63-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

BAMIFYLLINE; 2016-63-9; Bamiphylline; Benzetamophylline; Bamifilina

IUPAC/Chemical Name

8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione

InChl Key

VVUYEFBRTFASAH-UHFFFAOYSA-N

InChl Code

InChI=1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/16229;

3D Conformer.

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