ARTEANNUIN
Artesunate is a watersoluble artemisinin derivative used for severe malaria. Benefits include rapid parasite clearance. Side effects include hemolysis, liver enzyme elevation, and fever. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of action
Arteannuin (arteannuin A) is a sesquiterpene lactone precursor found in Artemisia annua, structurally related to artemisinin. Although arteannuin itself has mild antimalarial activity, it is primarily significant as a biosynthetic precursor in the artemisinin pathway. Its mechanism involves weak mitochondrial and haemassociated disruption in Plasmodium species.
Benefits and advantages
Crucial for artemisinin biosynthesis research, metabolic engineering in Artemisia species, precursor isolation, and structuralactivity studies. Important in modelling semisynthetic artemisinin production routes.
Side effects and risks
Low acute toxicity but may cause irritation or hepatic enzyme induction at high doses. Handle as a bioactive phytochemical.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H22O5 |
|---|---|
| Molecular Weight | 282.33 g/mol |
| CAS Number | 63968-64-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | artemisinin; Qinghaosu; 63968-64-9; Huanghuahaosu; (+)-Artemisinin |
| IUPAC/Chemical Name | (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one |
| InChl Key | BLUAFEHZUWYNDE-NNWCWBAJSA-N |
| InChl Code | InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 |
| References |
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