ARTEANNUIN

Artesunate is a watersoluble artemisinin derivative used for severe malaria. Benefits include rapid parasite clearance. Side effects include hemolysis, liver enzyme elevation, and fever. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of action

Arteannuin (arteannuin A) is a sesquiterpene lactone precursor found in Artemisia annua, structurally related to artemisinin. Although arteannuin itself has mild antimalarial activity, it is primarily significant as a biosynthetic precursor in the artemisinin pathway. Its mechanism involves weak mitochondrial and haemassociated disruption in Plasmodium species.

Benefits and advantages

Crucial for artemisinin biosynthesis research, metabolic engineering in Artemisia species, precursor isolation, and structuralactivity studies. Important in modelling semisynthetic artemisinin production routes.

Side effects and risks

Low acute toxicity but may cause irritation or hepatic enzyme induction at high doses. Handle as a bioactive phytochemical.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H22O5

Molecular Weight

282.33 g/mol

CAS Number

63968-64-9

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

artemisinin; Qinghaosu; 63968-64-9; Huanghuahaosu; (+)-Artemisinin

IUPAC/Chemical Name

(1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

InChl Key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

InChl Code

InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/68827;

3D Conformer.

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