ANISOTROPINE METHYLBROMIDE
Anisotropine methylbromide is an anticholinergic agent that reduces gastrointestinal motility and secretions. It is used for peptic ulcer and IBS symptoms. Side effects include dry mouth, blurred vision, constipation, and urinary retention.
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Product Description
Mechanism of action
Anisotropine methylbromide is an anticholinergic agent acting as a competitive antagonist at muscarinic acetylcholine receptors (M1–M3). By blocking parasympathetic neural influence, it reduces gastrointestinal motility and secretions.
Benefits and advantages
Used in research focused on muscarinic receptor mapping, gastrointestinal motility modulation, and autonomic neuroscience. It also serves as a reference compound in antispasmodic drug development.
Side effects and risks
Expected risks include tachycardia, urinary retention, blurred vision, and CNS effects if absorbed. Handle as a potent anticholinergic agent.
Datasheet
| Molecular Formula | C21H26BrNO4 |
|---|---|
| Molecular Weight | 362.3 g/mol |
| CAS Number | 80-50-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | SOL IN WATER, CHLOROFORM; SPARINGLY SOL IN ALCOHOL; SLIGHTLY SOL IN ACETONE; INSOL IN ETHER |
| Purity | Purity information is available upon request (COA). |
| Synonym | ANISOTROPINE METHYLBROMIDE; Octatropine methylbromide; 80-50-2; Valpin; Valpin 50 |
| IUPAC/Chemical Name | [(1S,5R)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-propylpentanoate bromide |
| InChl Key | QSFKGMJOKUZAJM-JXMYBXCISA-M |
| InChl Code | InChI=1S/C17H32NO2.BrH/c1-5-7-13(8-6-2)17(19)20-16-11-14-9-10-15(12-16)18(14,3)4;/h13-16H,5-12H2,1-4H3;1H/q+1;/p-1/t14-,15+,16?; |
| References |
3D Conformer.
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