Tiratricol
Tiratricol, also known as TRIAC, is a thyroid hormone analogue used in endocrine and thyroid-hormone receptor research. It can activate thyroid hormone receptors and is studied for T3-like signalling, transport and metabolism. Potential risks include sweating, tremor, palpitations, anxiety, weight loss and heat intolerance. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Tiratricol, also known as TRIAC or triiodothyroacetic acid, is a thyroid hormone analogue structurally related to triiodothyronine. It can activate thyroid hormone receptors and is studied for its thyromimetic effects and tissue-specific handling in endocrine pharmacology.
Benefits and Advantages
Tiratricol is relevant for thyroid-hormone receptor research, endocrine drug development, analytical reference work and investigations involving thyroid hormone transport, metabolism and receptor activation. Its profile supports specialist studies where T3-like signalling is evaluated under controlled conditions.
Side Effects and Risks
Potential risks resemble excessive thyroid hormone exposure and may include sweating, tremor, palpitations, anxiety, weight loss, heat intolerance and effects on cardiovascular or metabolic status. Strict professional oversight and regulatory control are required for any development or supply activity.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C14H9I3O4 |
|---|---|
| Molecular Weight | 621.93 g/mol |
| CAS Number | 51-24-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Soluble in DMSO; limited aqueous solubility. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Tiratricol; 3,3',5-Triiodothyroacetic acid; TRIAC; Triac; Liothyroacetic acid |
| IUPAC/Chemical Name | 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid |
| InChl Key | UOWZUVNAGUAEQC-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20) |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/5803; small-molecule |
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