Artenimol
Artenimol, also known as dihydroartemisinin, is an artemisinin derivative used in antimalarial and peroxide-bioactivation research. Its endoperoxide bridge can generate reactive intermediates in haem- or iron-rich environments. Possible risks include gastrointestinal symptoms, headache, dizziness and hypersensitivity reactions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Artenimol, also known as dihydroartemisinin, is an artemisinin derivative containing an endoperoxide bridge. Activation by haem or iron-rich environments can generate reactive intermediates that damage parasite proteins and membranes in malaria-related pharmacological models.
Benefits and Advantages
Artenimol is valuable in antimalarial research, artemisinin-derivative comparison, formulation development and studies of peroxide-mediated bioactivation. Its potent activity profile supports analytical, stability and combination-product investigations under controlled pharmaceutical conditions.
Side Effects and Risks
Potential risks include gastrointestinal symptoms, headache, dizziness, hypersensitivity reactions and concerns related to resistance development or inappropriate exposure. As an active antimalarial compound, it must be handled under qualified professional and regulatory conditions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C15H24O5 |
|---|---|
| Molecular Weight | 284.35 g/mol |
| CAS Number | 71939-50-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Soluble in DMSO; solubility depends on solvent and conditions. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Artenimol; Dihydroartemisinin; Dihydroqinghaosu; DHA; Cotexin |
| IUPAC/Chemical Name | (4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol |
| InChl Key | BJDCWCLMFKKGEE-KXTPALSWSA-N |
| InChl Code | InChI=1S/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3/t8-,9-,10+,12+,13-,15-/m1/s1 |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/3000518; small-molecule |
3D Conformer.
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