RUXOLITINIB PHOSPHATE
Ruxolitinib Phosphate is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological Characteristics Experimental behavior is governed by solubility, stability, ionization state, and matrix interactions. Proper formulation control is essential. Mechanism of Action No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent. It is primarily applied to investigate compound-specific mechanisms, physicochemical behavior, and analytical or formulation-relevant characteristics under controlled laboratory conditions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Chemical & Pharmacological Characteristics
Experimental behavior is governed by solubility, stability, ionization state, and matrix interactions. Proper formulation control is essential.
Mechanism of Action
No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent.
Interpretation should include matched controls to separate direct chemical effects from secondary stress responses.
Advanced
- Analytical reference and quality control
- Formulation development and stability screening
- Compatibility testing with excipients and packaging
- Comparative toxicology benchmarking
- Documentation support for R&D workflows
Toxicodynamics & Cellular Hazard Spectrum
- Nonspecific cytotoxicity at high exposure
- Solubility or aggregation artifacts
- Matrix-dependent assay interference
- Handling-related irritation risk
- Dispose according to laboratory waste regulations
For expert laboratory research only – not intended for biological or therapeutic exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H21N6O4P |
|---|---|
| Molecular Weight | 404.4 g/mol |
| CAS Number | 1092939-17-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Ruxolitinib phosphate; 1092939-17-7; Jakafi; ruxolitinib monophosphate; INCB018424 PHOSPHATE |
| IUPAC/Chemical Name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid |
| InChl Key | JFMWPOCYMYGEDM-XFULWGLBSA-N |
| InChl Code | InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1 |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/25127112; small-molecule |
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