VENTOCLAX
Ventoclax is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological Characteristics Experimental behavior is governed by solubility, stability, ionization state, and matrix interactions. Proper formulation control is essential. Mechanism of Action No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent. It is primarily applied to investigate compound-specific mechanisms, physicochemical behavior, and analytical or formulation-relevant characteristics under controlled laboratory conditions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Chemical & Pharmacological Characteristics
Experimental behavior is governed by solubility, stability, ionization state, and matrix interactions. Proper formulation control is essential.
Mechanism of Action
No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent.
Interpretation should include matched controls to separate direct chemical effects from secondary stress responses.
Advanced
- Analytical reference and quality control
- Formulation development and stability screening
- Compatibility testing with excipients and packaging
- Comparative toxicology benchmarking
- Documentation support for R&D workflows
Toxicodynamics & Cellular Hazard Spectrum
- Nonspecific cytotoxicity at high exposure
- Solubility or aggregation artifacts
- Matrix-dependent assay interference
- Handling-related irritation risk
- Dispose according to laboratory waste regulations
For expert laboratory research only – not intended for biological or therapeutic exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C45H50ClN7O7S |
|---|---|
| Molecular Weight | 868.4 g/mol |
| CAS Number | 1257044-40-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Venetoclax; 1257044-40-8; ABT-199; Venclexta; GDC-0199 |
| IUPAC/Chemical Name | 4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide |
| InChl Key | LQBVNQSMGBZMKD-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54) |
| References | small-molecule |
3D Conformer.
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