TICARCILLIN

Ticarcillin is a broadspectrum penicillin effective against gramnegative bacteria. Often combined with clavulanate. Side effects include rash, diarrhea, electrolyte imbalance, and hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 0417a0a6a095 Category: Tag:

Product Description


Mechanism of Action

TICARCILLIN exerts multiaxis biochemical modulation involving enzymaticcascade interference, receptormediated signalling adjustment, oxidativestress balancing, mitochondrialrespiratory modulation, ionchannel behaviour influence, cytoskeletalarchitecture modification and transcriptionfactor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membraneanchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP/DAG turnover, cAMP regulation, ATP flux and cellular redoxstate stability.

Benefits & Applications

  • Receptorligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multiomics integration research
  • Cytoskeletal and membranedynamics analysis
  • Apoptosis, autophagy and survivalpathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidativestress imbalance
  • Mitochondrial overload or ETC suppression
  • Ionchannel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dosedependent cytotoxicity
  • Inflammatory cascade activation

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H16N2O6S

Molecular Weight

384.4 g/mol

CAS Number

34787-01-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

7.16e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

TICARCILLIN; 34787-01-4; Ticarcilline; Ticarcilina; Ticarcillinum

IUPAC/Chemical Name

(2S,5R,6R)-6-[[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

OHKOGUYZJXTSFX-KZFFXBSXSA-N

InChl Code

InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/36921;

3D Conformer.

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